Beta-lactam Antibiotics

β-lactam antibiotics are characterized by four-membered ß-lactam ring. Penicillin G was the first β-lactam antibiotic that entered the clinic. Almost all ß-lactam antibiotics derived initially from microbes through a fermentation process. β-lactam antibiotics are bactericidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls. The activity of these antibiotics is related to the opening of the ß-lactam ring. These antibiotics have broad antibacterial spectrum, strong antibacterial activity, low toxicity, high industrial level, clear structure-activity relationship, and high alterability, so they have been widely developed and applied.

Beta-lactam Antibiotics (15):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-13678

Meropenem	96036-03-2	99.85%
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant *N. gonorrhoeae* (MIC value of 0.02-0.06 mg/mL), *H. influenzae* (MIC value of 0.03-0.12 mg/mL), and *H. ducreyi* (MIC value of 0.015-0.12 mg/mL).

HY-B1418

Tazobactam	89786-04-9	99.94%
Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research.

HY-B1463

Penicillin G sodium salt	69-57-8	98.06%
Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-B0975

Penicillin V Potassium	132-98-9	99.01%
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.

HY-B1463R

Penicillin G sodium salt (Standard)	69-57-8
Penicillin G sodium salt (Standard) is the analytical standard of Penicillin G sodium salt. This product is intended for research and analytical applications. Penicillin G sodium salt is a typical β-lactam antibiotic.

HY-13678R

Meropenem (Standard)	96036-03-2
Meropenem (Standard) is the analytical standard of Meropenem. This product is intended for research and analytical applications. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL).

HY-N11247

Agrocin 84	59111-78-3
Agrocin 84 is a microbial metabolite that inhibits DNA and protein synthesis and amino acid transport in a susceptible, virulent strain of A. tumefaciens H-38-9.

HY-N14226

Eurystatin B	137563-64-5
Eurystatin B is a prolyl endopeptidase (PED) inhibitor. Eurystatin B has a protective effect during Scopolamine (HY-N0296)-induced amnesia in rats.

HY-122955

Xanthobaccin A	227596-81-8
Xanthobaccin A is an antifungal compound, can be isolated from the culture fluid of Stenotrophomonas sp. strain SB-K88. Xanthobaccin A has potent inhibitory effect on sugar beet damping-off disease.

HY-B0975R

Penicillin V Potassium (Standard)	132-98-9
Penicillin V (Potassium) (Standard) is the analytical standard of Penicillin V (Potassium). This product is intended for research and analytical applications. Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.

HY-117108

Nocardicin A	39391-39-4
Nocardicin A is a beta-lactam antibiotic with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast.

HY-B0030R

D-Cycloserine (Standard)	68-41-7
D-Cycloserine (Standard) is the analytical standard of D-Cycloserine. This product is intended for research and analytical applications. D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research.

HY-120572

PI-091	129051-63-4
PI-091 is a platelet aggregation inhibitor, and can be used for researching platelet aggregation.

HY-121120

Isosulfazecin	77900-75-5
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics.

HY-B1418R

Tazobactam (Standard)	89786-04-9
Tazobactam (Standard) is the analytical standard of Tazobactam. This product is intended for research and analytical applications. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research.

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